Reset the Rhythm, Reclaim Your Life: AF Awareness Week 17 – 23 November 2025

Atrial Fibrillation (AF) is the most common heart rhythm disorder in Europe^[1], affecting an estimated 11 million people,^[2] yet it remains underdiagnosed.^[3] Many people delay seeking medical advice, dismissing symptoms until complications arise or their diagnosis is missed by health care professionals due to not being screened for AF.^[4] As AF progresses, it can have a significant impact on quality of life, leading to increased discomfort and emotional distress.^[5] Importantly, AF increases stroke risk by up to five times, and AF-related strokes are often more severe and disabling. AF is also associated with a three-fold increased risk of developing heart failure. ^[6] Education, timely diagnosis and effective management are essential for improving outcomes and enhancing quality of life in persons with atrial fibrillation.^[7]

As part of Daiichi Sankyo Europe’s ongoing commitment to advancing cardiovascular care, and in recognition of Global AF Aware Week #GAFAW2025 led by the AF Association, part of Arrhythmia Alliance, we are proud to amplify the theme “Reset the Rhythm, Reclaim Your Life.”

Learning from patients: Insights from an Advisory Board on Quality of Life for People Living with AF

To better understand the impact of AF, Daiichi Sankyo Europe partnered with the AF Association to co-design and run an Advisory Board to learn from people living with AF about their lives with the condition. Their perspectives revealed both the challenges and opportunities in improving AF care, from early diagnosis and communication to emotional support and shared decision-making.^[8]

Physical Experience of AF

The physical experience of AF varies widely among individuals - from being completely asymptomatic to experiencing severe or life-altering symptoms. Common manifestations include palpitations, shortness of breath, dizziness, and fatigue. Participants reported a wide range of physical experiences with AF, including palpitations, breathlessness, and fatigue, although some were asymptomatic. The severity of symptoms varied among individuals, reflecting the diverse ways AF can affect daily life.^[8]

Psychological Burden

AF is not only a physical condition but also carries a considerable psychological burden. The unpredictable nature of AF episodes can cause anxiety, uncertainty, and disruption to daily life. Many people described a considerable psychological burden associated with AF, including stress, anxiety about health risks, and feelings of frustration or helplessness due to unknown triggers.^[8]

Emotional and Social Interactions

AF can influence emotional wellbeing and day-to-day interactions. Living with a long-term, unpredictable condition may affect confidence and participation in normal routines. Patients often need time and support to adapt, build resilience, and maintain a sense of normality while managing AF. ^[8]

AF (Un)awareness and Education

Despite affecting millions across Europe, AF often goes unnoticed. Many individuals are unaware they have the condition, as symptoms may be intermittent, subtle, or mistaken for other health issues. The Advisory Board highlighted that both patients and HCPs may lack awareness and education about AF prior to diagnosis, emphasising the need for clear, accessible information about AF, its implications, and management. ^[8]

AF Management

AF management is complex, with experiences and perceptions differing among patients. While many find treatment beneficial, others may struggle with adherence due to factors such as side effects, pill burden, or lack of symptoms. Providing education and ongoing support can encourage adherence and improve outcomes. ^[8]

Patient-Doctor Relationship

Interactions with HCPs are generally positive, but some patients experience dissatisfactory care during their initial interaction. Greater accessibility and patient involvement in decision-making is needed. ^[8]

A Collaborative Path Forward

Improving AF care requires a united effort. Patients, healthcare professionals, advocacy organisations, and industry partners must work together to build a more coordinated, patient-centred approach.

Shared decision-making improves confidence, adherence to therapy, and overall satisfaction with care. When patients and their care teams work in partnership, it can lead to:^[9]

• Greater understanding of AF and its management
• Increased awareness by the health care team of your priorities and goals
• Increased confidence and adherence to treatment
• Reduced uncertainty and concern
• Improved cardiovascular outcomes

Our Commitment

At Daiichi Sankyo Europe, we are dedicated to supporting initiatives that raise awareness, promote early diagnosis, and improve the lives of those affected by AF. By encouraging open dialogue and collaboration across the healthcare community, we aim to foster a favourable environment for the management and promotion of heart health.